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KMID : 0378019640070040100
New Medical Journal
1964 Volume.7 No. 4 p.100 ~ p.111
Anatomical Studies on the Brown Adipose Tissue of Rodents


Abstract
Histogenesis of the interscapular brown adipose tissue of mice was observed histologically.
Fetuses ranging from ten days to birth were used.
At eleven days of gestation, the Anlage of the interscapular brown adipose tissue was found as characteristic vascular networks, in the subcutaneous layer of the upper dorsolateral aspect of the body.
A small mass of mesenchymal cells around a capillary network hypertrophied, and developed into the ovoid or polygonal primitive brown fat cells, at eleven days of gestation.
Primitive brown fat cells continued to form small vacuoles at thirteen days of gestation, and to gro primitive lobules encircled by thin anastomosing mesenchymal cells at fourteen days.
The appearance of small sudanophilic droplets in the primitive brown fat cells was, also seen at "f teen days gestation.
The Anlage of white adipose tissue was initially observed as a small mass of young fat cells, wb~ differed from mesenchymal cells in the subcutis, and all of ¢¥the body.
The most characteristic difference between borwn and white adipose tissues was the Anlage, which.of the latter was not proceeded by a capillary network.
From these findings, it was concluded that, from a histogenetical point of view, the typical brown adipose tissue(interscapular) is essentially different in character from white adipose tissue. It was noticed that there is no direct transitional form between two kinds of the adipose tissue.
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